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Peri-implant infections of oral biofilm etiology.

Forskningsöversiktsartikel
Författare Georgios N Belibasakis
Georgios Charalampakis
Nagihan Bostanci
Bernd Stadlinger
Publicerad i Advances in experimental medicine and biology
Volym 830
Sidor 69-84
ISSN 0065-2598
Publiceringsår 2015
Publicerad vid Institutionen för odontologi
Sidor 69-84
Språk en
Länkar dx.doi.org/10.1007/978-3-319-11038-...
Ämneskategorier Klinisk medicin, Oral mikrobiologi

Sammanfattning

Biofilms are complex microbial communities that grow on various surfaces in nature. The oral micobiota tend to form polymicrobial biofilms, particularly on the hard mineralized surfaces of teeth, which may impact on oral health and disease. They can cause inflammation of the adjacent tooth-supporting (periodontal) tissues, leading to destructive periodontal disease and tooth loss. The emergence of osseointegrated dental implants as a restorative treatment option for replacing missing teeth has also brought along new artificial surfaces within the oral cavity, on which oral bacteria can form biofilms. As in the case of natural teeth, biofilms on implant surfaces may also trigger infection and cause inflammatory destruction of the peri-implant tissue (i.e. peri-implantitis). While there are strong similarities in the composition of the mixed microbial flora between periodontal and peri-implant infections, there are also a few distinctive differences. The immunological events underlying the pathogenesis of peri-implant infections are qualitatively similar, yet more extensive, compared to periodontal infections, resulting in a faster progression of tissue destruction. This chapter summarizes the current knowledge on the microbiology and immunology of peri-implant infections, including findings from the peri-implant crevicular fluid, the inflammatory exudate of the peri-implant tissue. Moreover, it discusses the diagnosis and current approaches for the treatment of oral infections.

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