Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Medicines, shaken and sti… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Medicines, shaken and stirred: a critical review on the ecotoxicology of pharmaceutical mixtures

Artikel i vetenskaplig tidskrift
Författare Thomas Backhaus
Publicerad i Philosophical Transactions of the Royal Society B-Biological Sciences
Volym 369
Nummer/häfte 1656
ISSN 0962-8436
Publiceringsår 2014
Publicerad vid Institutionen för biologi och miljövetenskap
Språk en
Länkar dx.doi.org/10.1098/rstb.2013.0585
Ämnesord mixture ecotoxicology, concentration addition, independent action, synergism, PERSONAL CARE PRODUCTS, ENVIRONMENTAL RISK-ASSESSMENT, WASTE-WATER, BACTERIAL COMMUNITIES, AQUATIC ENVIRONMENT, SINGLE-SUBSTANCE, VIBRIO-FISCHERI, STP EFFLUENTS, TOXICITY, RIVER, Biology
Ämneskategorier Biologiska vetenskaper, Toxikologi

Sammanfattning

Analytical monitoring surveys routinely confirm that organisms in the environment are exposed to complex multi-component pharmaceutical mixtures. We are hence tasked with the challenge to take this into consideration when investigating the ecotoxicology of pharmaceuticals. This review first provides a brief overview of the fundamental approaches for mixture toxicity assessment, which is then followed by a critical review on the empirical evidence that is currently at hand on the ecotoxicology of pharmaceutical mixtures. It is concluded that, while the classical concepts of concentration addition and independent action (response addition) provide a robust scientific footing, several knowledge gaps remain. This includes, in particular, the need for more and better empirical data on the effects of pharmaceutical mixtures on soil organisms as well as marine flora and fauna, and exploring the quantitative consequences of toxicokinetic, toxicodynamic and ecological interactions. Increased focus should be put on investigating the ecotoxicology of pharmaceutical mixtures in environmentally realistic settings.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?