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Does change in hip circumference predict cardiovascular disease and overall mortality in Danish and Swedish women?

Artikel i vetenskaplig tidskrift
Författare Anne Lanfer
Kirsten Mehlig
BL Heitmann
Lauren Lissner
Publicerad i Obesity
Volym 22
Nummer/häfte 3
Sidor 957–963
ISSN 1930-7381
Publiceringsår 2014
Publicerad vid Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa
Sidor 957–963
Språk en
Länkar dx.doi.org/10.1002/oby.20604
Ämneskategorier Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi

Sammanfattning

Abstract OBJECTIVE: Accumulating evidence consistently shows that small hip circumference (HC) is related to increased risk of cardiovascular disease (CVD), coronary heart disease, diabetes, and premature death in women. This study aims to clarify whether this inverse association can be found in both normal- and overweight individuals and if change in HC over time relates to morbidity and mortality risk. DESIGN AND METHODS: HC and 6-year change in HC in relation to the risk for all-cause mortality and CVD morbidity and mortality was investigated in a pooled sample of 2,867 women from the DANISH MONICA study and the Prospective Population Study of Women in Gothenburg with a total of 66,627 person-years of follow-up. RESULTS: Baseline HC was significantly and inversely associated with all-cause and CVD-specific mortality after adjustment for BMI, waist circumference (WC), and other covariates. In stratified analyses, the inverse association was weaker in women with a BMI of more than 25 kg/m2 . Six-year change in hip size was not associated with mortality or morbidity endpoints. CONCLUSIONS: Our results imply the existence of a basal risk associated with small hip size, which is, however, independent from changes in gluteofemoral body mass and therefore unlikely to be modifiable.

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