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Oral infections and their influence on medical rehabilitation in kidney transplant patients.

Artikel i vetenskaplig tidskrift
Författare Kerstin Schander
Mats Jontell
Peter Johansson
Gunnela Nordén
Magnus Hakeberg
John Bratel
Publicerad i Swedish dental journal
Volym 33
Nummer/häfte 3
Sidor 97-103
ISSN 0347-9994
Publiceringsår 2009
Publicerad vid Institutionen för odontologi
Sidor 97-103
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Adolescent, Adult, Aged, Candidiasis, Oral, complications, Female, Graft Rejection, etiology, microbiology, Humans, Immunocompromised Host, Kidney Transplantation, immunology, rehabilitation, Male, Middle Aged, Opportunistic Infections, complications, microbiology, Periodontitis, complications, microbiology, Risk Factors, Stomatitis, complications, microbiology, Stomatitis, Herpetic, complications, Young Adult
Ämneskategorier Övrig odontologi

Sammanfattning

Infections seem to be the most common life-threatening complication of long-term immunosuppressive therapy following organ transplantation. Although sparse scientific evidence, potential oral infections are considered to contribute to these complications. The aim of this study was to examine whether there is an association between oral infections and rejections after kidney transplantation. A group of 46 kidney transplant candidates was enrolled. The patients were examined clinically and radiographically for dental caries, periodontal disease, mucosal lesions/infections, and general oral health problems. Examinations were conducted the day before transplantation, and one year post transplantation. Fifteen (32.6%) patients developed acute rejections during the first year. Six of these patients (40%) presented with oral opportunistic infections (candida or herpes infections of the oral mucosa). The number of dental infections and semi-impacted teeth were low. When rejections were related to probing pocket depths (PPDs) > or = 4 mm and apical lesions together, statistical significance was not reached (p=0.075, OR=3.17 [0.87; 11.55]). Similar results were obtained when PPDs > or = 4 mm, apical lesions, semi-impacted teeth, and opportunistic mucosal infections were compared to rejections. The results of the present study do not support that opportunistic oral mucosal infections or dental-related infections seem to increase the risk of rejection in kidney transplanted patients.

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