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Ridge preservation with the use of Bio-Oss collagen: A 6-month study in the dog.

Artikel i vetenskaplig tidskrift
Författare Mauricio G Araújo
Jan Lindhe
Publicerad i Clinical oral implants research
Volym 20
Nummer/häfte 5
Sidor 433-40
ISSN 1600-0501
Publiceringsår 2009
Publicerad vid Institutionen för odontologi
Sidor 433-40
Språk en
Länkar dx.doi.org/10.1111/j.1600-0501.2009...
Ämnesord Alveolar Bone Loss, prevention & control, Alveolar Process, drug effects, physiology, Animals, Biocompatible Materials, Bone Matrix, physiology, Bone Regeneration, drug effects, physiology, Bone Remodeling, drug effects, physiology, Bone Substitutes, pharmacology, Dogs, Follow-Up Studies, Minerals, pharmacology, Oral Surgical Procedures, methods, Tooth Extraction, adverse effects, Tooth Socket, drug effects, physiology, Wound Healing, drug effects, physiology
Ämneskategorier Parodontologi

Sammanfattning

BACKGROUND: In previous short-term studies, it was observed that while the placement of biomaterial in alveolar sockets may promote bone formation and ridge preservation, the graft may in fact also delay healing. AIM: The objective of the present experiment was to evaluate the more long-term effect on hard tissue formation and the amount of ridge augmentation that can occur by the placement of a xenogeneic graft in extraction sockets of dogs. MATERIAL AND METHODS: Five beagle dogs were used. The third mandibular premolars were hemi-sected. The distal roots were carefully removed. A graft consisting of Bio-Oss collagen was placed in one socket while the contra-lateral site was left without grafting. After 6 months of healing, the dogs were euthanized and biopsies were sampled. From each experimental site, four ground sections - two from the mesial root and two from the healed socket - were prepared, stained and examined under a microscope. RESULTS: The placement of Bio-Oss collagen in the fresh extraction socket served as a scaffold for tissue modeling but did not enhance new bone formation. In comparison with the non-grafted sites, the dimension of the alveolar process as well as the profile of the ridge was better preserved in Bio-Oss-grafted sites. CONCLUSION: The placement of a biomaterial in an extraction socket may modify modeling and counteract marginal ridge contraction that occurs following tooth removal.

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