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Similar cost-utility for double- and single-bundle techniques in ACL reconstruction

Artikel i vetenskaplig tidskrift
Författare Ninni Sernert
Elisabeth K Hansson
Publicerad i Knee Surgery, Sports Traumatology, Arthroscopy
Volym 26
Nummer/häfte 2
Sidor 634-647
ISSN 0942-2056
Publiceringsår 2017
Publicerad vid Institutionen för vårdvetenskap och hälsa
Institutionen för kliniska vetenskaper, Avdelningen för ortopedi
Sidor 634-647
Språk en
Länkar dx.doi.org/10.1007/s00167-017-4725-...
Ämnesord ACL injury, HRQoL, ICER, QALY, Sensitivity analyses, Single- and double-bundle technique
Ämneskategorier Ortopedi

Sammanfattning

© 2017 The Author(s) Purpose: The aim was to estimate the cost-utility of the DB technique (n = 53) compared with the SB (n = 50) technique 2 years after ACL reconstruction. Methods: One hundred and five patients with an ACL injury were randomised to either the Double-bundle (DB) or the Single-bundle (SB) technique. One hundred and three patients (SBG n = 50, DBG n = 53) attended the 2-year follow-up examination. The mean age was 27.5 (8.4) years in the SBG and 30.1 (9.1) years in the DBG. The cost per quality-adjusted life years (QALYs) was used as the primary outcome. Direct costs were the cost of health care, in this case outpatient procedures. Indirect costs are costs related to reduce work ability for health reasons. The cost-utility analysis was measured in terms of QALY gained. Results: The groups were comparable in terms of clinical outcome. Operating room time was statistically significantly longer in the DBG (p = 0.001), making the direct costs statistically significantly higher in the DBG (p = 0.005). There was no significant difference in QALYs between groups. In the cost-effectiveness plane, the mean difference in costs and QALYs from the trial data using 1000 bootstrap replicates in order to visualise the uncertainty associated with the mean incremental cost-effectiveness ratio (ICER) estimate showed that the ICERs were spread out over all quadrants. The cost-effectiveness acceptability curve showed that there was a 50% probability of the DB being cost-effective at a threshold of Euro 50,000. Conclusion: The principal findings are that the DB is more expensive from a health-care perspective. This suggests that the physician may choose individualised treatment to match the patients’ expectations and requirements.

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