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Guidelines--are they useful?

Journal article
Authors Elinor Ben-Menachem
Jacqueline A French
Published in Epilepsia
Volume 47
Issue Suppl 1
Pages 62-4
ISSN 0013-9580
Publication year 2006
Published at Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Pages 62-4
Language en
Keywords Anticonvulsants, economics, therapeutic use, Clinical Trials as Topic, statistics & numerical data, Cost-Benefit Analysis, Epilepsy, drug therapy, economics, Evidence-Based Medicine, statistics & numerical data, Humans, Outcome Assessment (Health Care), methods, Physician's Practice Patterns, economics, standards, Practice Guidelines as Topic, standards, Professional Practice, economics, standards, Randomized Controlled Trials as Topic, statistics & numerical data
Subject categories Neurology


Antiepileptic drug (AED) guidelines are developed to improve medical decision making, to provide guidance and recommendation for patient management, to develop standards to judge or assess clinical practice, and to keep the cost-benefit ratio at an acceptable level. These guidelines are derived from evidence-based medicine (EBM), a four-tiered grading system that is used to analyze clinical trials and published experiments independent of clinical bias and experience. Although guidelines may not answer all questions it is critical that clinicians using them consider the available evidence, as well as the quality of the evidence, when incorporating the information in their decision making.

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