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Adolescent-onset anorexia nervosa: 18-year outcome.

Journal article
Authors Elisabet Wentz
I Carina Gillberg
Henrik Anckarsäter
Christopher Gillberg
Maria Råstam
Published in British Journal of Psychiatry
Volume 194
Issue 2
Pages 168-174
ISSN 0007-1250
Publication year 2009
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Pages 168-174
Language en
Keywords Adolescent, Age of Onset, Anorexia Nervosa, Epidemiology, Case-Control Studies, Chronic Disease, Comorbidity, Female, Follow-Up Studies, Humans, Male, Mood Disorders, Epidemiology, Outcome Assessment (Health Care), Statistics & numerical data, Patient Acceptance of Health Care, Statistics & numerical data, Social Adjustment, Young Adult
Subject categories Child and adolescent psychiatry


BACKGROUND: The long-term outcome of anorexia nervosa is insufficiently researched. AIMS: To study prospectively the long-term outcome and prognostic factors in a representative sample of people with teenage-onset anorexia nervosa. METHOD: Fifty-one people with anorexia nervosa, recruited by community screening and with a mean age at onset of 14 years were compared with 51 matched comparison individuals at a mean age of 32 years (18 years after disorder onset). All participants had been examined at ages 16 years, 21 years and 24 years. They were interviewed for Axis I psychiatric disorders and overall outcome (Morgan-Russell assessment schedule and the Global Assessment of Functioning). RESULTS: There were no deaths. Twelve per cent (n=6) had a persisting eating disorder, including three with anorexia nervosa. Thirty-nine per cent of the anorexia nervosa group met the criteria for at least one psychiatric disorder. The general outcome was poor in 12%. One in four did not have paid employment owing to psychiatric problems. Poor outcome was predicted by premorbid obsessive-compulsive personality disorder, age at onset of anorexia nervosa and autistic traits. CONCLUSIONS: The 18-year outcome of teenage-onset anorexia nervosa is favourable in respect of mortality and persisting eating disorder.

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