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Tracing of norovirus outbreak strains in mussels collected near sewage effluents.

Journal article
Authors Nancy P Nenonen
Charles Hannoun
Peter Horal
Bodil Hernroth
Tomas Bergström
Published in Applied and environmental microbiology
Volume 74
Issue 8
Pages 2544-9
ISSN 1098-5336
Publication year 2008
Published at Institute of Biomedicine, Department of Infectious Medicine
Department of Marine Ecology
Pages 2544-9
Language en
Keywords Animals, Bivalvia, virology, Caliciviridae Infections, epidemiology, virology, Disease Outbreaks, Epidemiology, Molecular, Humans, Molecular Sequence Data, Norovirus, classification, genetics, isolation & purification, Phylogeny, RNA, Viral, genetics, Sequence Analysis, DNA, Sequence Homology, Sewage, Sweden
Subject categories Microbiology in the medical area


Noroviruses from mussels collected near sewage effluents were compared with local patient outbreak strains. Sequence analyses of RNA polymerase-capsid-poly(A)-3' (3.1-kilobase) regions confirmed the 99.9% similarity between genotype I.1 strains from mussels and patient strains from recreational-bathing outbreaks, indicating the potential usefulness of sentinel norovirus mussel studies in tracing human norovirus contamination of coastal waters.

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