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Neurobiological processes in alcohol addiction.

Review article
Authors A D Lê
K Kiianmaa
C L Cunningham
Jörgen Engel
Mia Ericson
Bo Söderpalm
G F Koob
A J Roberts
F Weiss
P Hyytiä
S Janhunen
J Mikkola
P Bäckström
I Ponomarev
J C Crabbe
Published in Alcoholism, clinical and experimental research
Volume 25
Issue 5 Suppl ISBRA
Pages 144S-151S
ISSN 0145-6008
Publication year 2001
Published at Institute of Physiology and Pharmacology
Institute of Clinical Neurosciences, Section of Psychiatry
Pages 144S-151S
Language en
Keywords Alcoholism, genetics, metabolism, Animals, Central Nervous System Depressants, pharmacology, Conditioning (Psychology), drug effects, physiology, Corticotropin-Releasing Hormone, metabolism, Drug Tolerance, Ethanol, pharmacology, Humans, Mice, Motor Activity, drug effects, physiology, Phenotype, Rats, Receptors, Corticotropin-Releasing Hormone, drug effects, metabolism, Receptors, GABA, drug effects, metabolism, Reinforcement (Psychology), Reward, Self Administration, Substance Withdrawal Syndrome, genetics, metabolism
Subject categories Pharmacology, Substance Abuse


This article represents the proceedings of a symposium at the ISBRA Meeting in Yokohama, Japan. The chairs were A. D. Lê and K. Kiianmaa. The presentations were (1) Alcohol reward and aversion, by C. L. Cunningham; (2) The role of sensitization of neuronal mechanisms in ethanol self-administration, by J. A. Engel, M. Ericson, and B. Söderpalm; (3) Alcohol self-administration in dependent animals: Neurobiological mechanisms, by G. F. Koob, A. J. Roberts, and F. Weiss; (4) Stress and relapse to alcohol, by A. D. Lê; (5) Alcohol-preferring AA and alcohol-avoiding ANA rats differ in locomotor activation induced by repeated morphine injections, by P. Hyytiä, S. Janhunen, J. Mikkola, P. Bäckström, and K. Kiianmaa; and (6) Initial sensitivity and acute functional tolerance to the hypnotic effects of ethanol in mice genetically selected for mild and severe ethanol withdrawal convulsions, by I. Ponomarev and J. C. Crabbe.

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