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Mechanisms of alcohol-nicotine interactions: alcoholics versus smokers.

Review article
Authors T Narahashi
Bo Söderpalm
Mia Ericson
Peter Olausson
Jörgen Engel
X Zhang
A Nordberg
W Marszalec
G L Aistrup
L G Schmidt
U Kalouti
M Smolka And
L Hedlund
Published in Alcoholism, clinical and experimental research
Volume 25
Issue 5 Suppl ISBRA
Pages 152S-156S
ISSN 0145-6008
Publication year 2001
Published at Institute of Physiology and Pharmacology
Institute of Physiology and Pharmacology, Dept of Pharmacology
Pages 152S-156S
Language en
Keywords Acetylcholine, pharmacology, Alcohol Deterrents, pharmacology, Alcoholism, drug therapy, metabolism, Animals, Central Nervous System Depressants, pharmacology, Drug Interactions, physiology, Ethanol, pharmacology, Gene Expression, physiology, Humans, Male, Nicotine, pharmacology, therapeutic use, Nicotinic Agonists, pharmacology, therapeutic use, Rats, Receptors, Nicotinic, metabolism, Recurrence, prevention & control, Reinforcement (Psychology), Smoking, metabolism, Taurine, analogs & derivatives, pharmacology, Vasodilator Agents, pharmacology, Ventral Tegmental Area, drug effects, metabolism
Subject categories Neurobiology, Substance Abuse


This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Toshio Narahashi and Bo Söderpalm. The presentations were (1) Nicotinic mechanisms and ethanol reinforcement: Behavioral and neurochemical studies, by Bo Söderpalm, M. Ericson, P. Olausson, and J. A. Engel; (2) Chronic nicotine and ethanol: Differential regulation in gene expression of nicotinic acetylcholine receptor subunits, by X. Zhang and A. Nordberg; (3) Nicotine-ethanol interactions at neuronal nicotinic acetylcholine receptors, by Toshio Narahashi, William Marszalec, and Gary L. Aistrup; (4) Relapse prevention in alcoholics by cigarette smoking? Treatment outcome in an observational study with acamprosate, by L.G. Schmidt, U. Kalouti, M. Smolka, and M. Soyka; and (5) Effect of nicotine on voluntary ethanol intake and development of alcohol dependence in male rats, by L. Hedlund and G. Wahlström.

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