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The Göteborg MCI study – absolute and normalized hippocampal volumes in the prediction of dementia

Poster
Authors Carl Eckerström
Erik Olsson
Sindre Rolstad
Åke Edman
Anders Wallin
Helge Malmgren
Published in The Annual General Meeting of the Swedish Society of Medicine, Nov. 28-30, 2007
Publication year 2007
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Department of Philosophy
Language en
Links hum.gu.se/institutioner/filosofi/pu...
Keywords Hippocampus, Volumetry, MCI (Mild Cognitive Disorder), Dementia, Alzheimer
Subject categories Radiology, Nuclear Medicine and Medical Imaging, Psychiatry

Abstract

Mild cognitive impairment (MCI) is a state where the cognitive functions are more impaired than what would be expected from aging alone but not enough to be described as dementia. In our material, there was an overrepresentation of men in the stable MCI group and an overrepre-sentation of women in the two other groups. Normalization of the data removed the gender-related differences in hippocampal volume and allowed for better utilization of the data. Hippocampal volumetry predicts conversion to dementia in MCI patients.

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