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Nodule detection in digital chest radiography: introduction to the RADIUS chest trial.

Journal article
Authors Magnus Båth
Markus Håkansson
Sara Börjesson
Susanne Kheddache
Anders Tingberg
Sören Mattsson
Lars Gunnar Månsson
Published in Radiation protection dosimetry
Volume 114
Issue 1-3
Pages 85-91
ISSN 0144-8420
Publication year 2005
Published at Institute of Selected Clinical Sciences, Department of Radiation Physics
Institute of Selected Clinical Sciences, Department of Radiology
Pages 85-91
Language en
Keywords Artifacts, Humans, Image Processing, Computer-Assisted, Lung, pathology, radiography, Lung Neoplasms, diagnosis, radiography, Models, Anatomic, Radiographic Image Interpretation, Computer-Assisted, methods, Radiography, methods, Radiography, Thoracic, methods, Software, X-Rays
Subject categories Radiology, Radiological physics


Most digital radiographic systems of today have wide latitude and are hence able to provide images with a small constraint on dose level. This opens up for an unprejudiced dose optimisation. However, in order to succeed in the optimisation task, good knowledge of the imaging and detection processes is needed. As a part of the European-wide research project 'unification of physical and clinical requirements for medical X-ray imaging'-governed by the Radiological Imaging Unification Strategies (RADIUS) Group-a major image quality trial was conducted by members of the group. The RADIUS chest trial was focused on the detection of lung nodules in digital chest radiography with the aims of determining to what extent (1) the detection of a nodule is dependent on its location, (2) the system noise disturbs the detection of lung nodules, (3) the anatomical noise disturbs the detection of lung nodules and (4) the image background and anatomical background act as pure noise for the detection of lung nodules. The purpose of the present paper is to give an introduction to the trial and describe the framework and set-up of the investigation.

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