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Microbiological evaluation of one- and two-visit endodontic treatment of teeth with apical periodontitis: a randomized, clinical trial.

Journal article
Authors Thomas Kvist
Anders Molander
Gunnar Dahlén
Claes Reit
Published in Journal of endodontics
Volume 30
Issue 8
Pages 572-6
ISSN 0099-2399
Publication year 2004
Published at Institute of Odontology
Institute of Odontology, Department of Oral Microbiology
Institute of Odontology, Department of Endodontology/Oral Diagnosis
Pages 572-6
Language en
Keywords Bacteria, Anaerobic, classification, drug effects, Calcium Hydroxide, therapeutic use, Colony Count, Microbial, Dental Pulp Cavity, microbiology, Female, Gram-Negative Facultatively Anaerobic Rods, drug effects, Humans, Iodine Compounds, therapeutic use, Male, Middle Aged, Periapical Periodontitis, microbiology, therapy, Porphyromonas endodontalis, drug effects, Porphyromonas gingivalis, drug effects, Potassium Iodide, therapeutic use, Prevotella, drug effects, Root Canal Irrigants, therapeutic use, Root Canal Therapy, methods
Subject categories Dentistry, Endodontology, Paedodontics


The antimicrobial efficacy of endodontic procedures performed in one-visit (including a 10-min intraappointment dressing with 5% iodine-potassium-iodide) was compared with a two-visit procedure (including an interappointment dressing with calcium-hydroxide paste). Teeth with apical periodontitis (n = 96) were randomly assigned to either group. Root canal sampling and culturing were performed before and immediately after instrumentation, and after medication. Initial sampling demonstrated the presence of microorganisms in 98% of the teeth. Postinstrumentation sampling showed reduction of cultivable microbiota. Antibacterial dressing further reduced the number of teeth with surviving microbes. In the postmedication samples, residual microorganisms were recovered in 29% of the one-visit teeth and in 36% of the two-visit treated teeth. No statistically significant differences between the groups were discerned. It was concluded that from a microbiological point of view, treatment of teeth with apical periodontitis performed in two appointments was not more effective than the investigated one-visit procedure.

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