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Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium

Journal article
Authors Johan Bylund
Åse Björstad
Daniel Granfeldt
Anna Karlsson
Charlotte Woschnagg
Claes Dahlgren
Published in J Biol Chem
Volume 278
Issue 33
Pages 30578-86
Publication year 2003
Published at Institute of Internal Medicine, Dept of Rheumatology and Inflammation Research
Pages 30578-86
Language en
Keywords Androstadienes/pharmacology, Antigens, CD/chemistry/metabolism, Calcium/*metabolism, Cytochalasin B/pharmacology, Cytoskeleton/drug effects/enzymology, Enzyme Activation/drug effects/physiology, Enzyme Inhibitors/pharmacology, GTP-Binding Proteins/metabolism, HL-60 Cells, Humans, NADPH Oxidase/*metabolism, Neutrophils/*enzymology, Platelet Membrane Glycoproteins/chemistry/metabolism, Protein Structure, Tertiary, Receptor, Anaphylatoxin C5a, Receptors, Cell Surface/chemistry/metabolism, Receptors, Complement/chemistry/metabolism, Receptors, Formyl Peptide, *Receptors, G-Protein-Coupled, Receptors, Immunologic/chemistry/*metabolism, Receptors, Interleukin-8A/chemistry/metabolism, Receptors, Interleukin-8B/chemistry/metabolism, Receptors, Peptide/chemistry/*metabolism, Signal Transduction/drug effects/physiology
Subject categories Medical and Health Sciences


In neutrophils, coupling of chemoattractants to their cell surface receptor at low temperature (

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