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Dementia Research Fit for the Planet: Reflections on Population Studies of Dementia for Researchers and Policy Makers Alike

Journal article
Authors C. E. Brayne
L. E. Barnes
M. M. B. Breteler
R. L. Brooks
C. Dufouil
C. Fox
L. Fratiglioni
M. A. Ikram
R. A. Kenny
M. Kivipelto
A. Lobo
M. Musicco
C. X. Qiu
E. Richard
S. G. Riedel-Heller
C. Ritchie
Ingmar Skoog
B. C. M. Stephan
A. Venneri
F. E. Matthews
Published in Neuroepidemiology
Volume 54
Issue 2
Pages 157-170
ISSN 0251-5350
Publication year 2020
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Pages 157-170
Language en
Keywords Guidelines, Population-based studies, Cohorts, Dementia, alzheimers-disease, cognitive function, prevalence, guidelines, standards, Public, Environmental & Occupational Health, Neurosciences & Neurology
Subject categories Neurosciences


In recent years, a rapidly increasing collection of investigative methods in addition to changes in diagnostic criteria for dementia have followed "high-tech" trends in medicine, with the aim to better define the dementia syndrome and its biological substrates, mainly in order to predict risk prior to clinical expression. These approaches are not without challenge. A set of guidelines have been developed by a group of European experts in population-based cohort research through a series of workshops, funded by the Joint Program for Neurodegenerative Disorders (JPND). The aims of the guidelines are to assist policy makers and researchers to understand (1) What population studies for ageing populations should encompass and (2) How to interpret the findings from population studies. Such studies are essential to provide evidence relevant to the understanding of healthy and frail brain ageing, including the dementia syndrome for contemporary and future societies by drawing on the past.

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