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A prospective study of perinatal and metabolic risk factors for early childhood caries

Journal article
Authors Katarina Boustedt
Josefine Roswall
Emma Kjellberg
S. Twetman
Jovanna Dahlgren
Published in Acta Paediatrica
Pages 6
ISSN 0803-5253
Publication year 2020
Published at Institute of Clinical Sciences, Department of Pediatrics
Pages 6
Language en
Keywords caries, glucose, metabolic syndrome, preterm birth, small for, gestational age, dental-caries, young-children, birth-weight, preterm, health, Pediatrics
Subject categories Pediatrics


Aim To study the relationship between early childhood caries and perinatal and metabolic risk factors in a cohort of preschool children. Methods The study population consisted of 208 children followed from birth to 6.5 years. We extracted the perinatal factors from medical records and questionnaires and assessed the occurrence of caries at the age of 5 years. Indicators of the metabolic syndrome (waist circumference, blood pressure, fasting insulin, glucose and dyslipidaemia) were recorded at 6.5 years of age. Results Infants born moderately to late preterm and infants born small for gestational age were more likely to have early childhood caries at 5 years of age (relative risk 4.2 and 2.3, respectively; P < .05). The presence of metabolic risk factors according to the IDEFICS monitoring levels did not differ between children with or without caries but a statistically significant correlation was found between the fasting glucose values and the number of decayed or filled teeth (r = 0.18; P < .05). Conclusion Being born preterm or small for gestational age increased the risk of early childhood caries. Preschool children with caries had higher fasting glucose levels but no other signs of the metabolic syndrome.

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