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Health-related quality of life among tonsillar carcinoma patients in Sweden in relation to treatment and comparison with quality of life among the population

Journal article
Authors Ali Adnan
A. Hogmo
M. Gebre-Medhin
G. Laurell
J. Reizenstein
L. Farnebo
L. S. Norberg
I. Notstam
E. Holmberg
Hedda Cange
Eva Hammerlid
Published in Head and Neck-Journal for the Sciences and Specialties of the Head and Neck
Volume 42
Issue 5
Pages 860-872
ISSN 1043-3074
Publication year 2020
Published at Institute of Clinical Sciences, Department of Oncology
Institute of Clinical Sciences, Department of Otorhinolaryngology
Pages 860-872
Language en
Keywords transoral robotic surgery, neck-cancer patients, european-organization, oropharyngeal cancer, eortc qlq-c30, reference-values, head, questionnaire, term, survivors, Otorhinolaryngology, Surgery
Subject categories Clinical Medicine


Background The health-related quality of life (HRQOL) of tonsillar carcinoma survivors was explored to investigate any HRQOL differences associated with tumor stage and treatment. The survivors' HRQOL was also compared to reference scores from the population. Methods In this exploratory cross-sectional study patients were invited 15 months after their diagnosis and asked to answer two quality of life questionnaires (EORTC QLQ- C30, EORTC QLQ- HN35), 405 participated. Results HRQOL was associated with gender, with males scoring better than females on a few scales. Patients' HRQOL was more associated with treatment than tumor stage. Patients' HRQOL was worse than that in an age- and sex-matched reference group from the normal population, the largest differences were found for problems with dry mouth followed by problems with sticky saliva, senses, swallowing and appetite loss. Conclusions The tonsillar carcinoma patients had a worse HRQOL compared to the general population one year after treatment.

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