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Chronic pain and health-related quality of life in women with autism And/or ADHD: A prospective longitudinal study

Journal article
Authors Karin Asztély
Svenny Kopp
Christopher Gillberg
Margda Waern
Stefan Bergman
Published in Journal of Pain Research
Volume 12
Pages 2925-2932
ISSN 1178-7090
Publication year 2019
Published at Institute of Medicine, School of Public Health and Community Medicine
Institute of Neuroscience and Physiology
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Gillberg Neuropsychiatry Centre
Pages 2925-2932
Language en
Links dx.doi.org/10.2147/JPR.S212422
Keywords Attention deficit disorder, Autism spectrum disorder, Female, Girls, Stimulants, Widespread pain, central stimulant agent, adult, analgesia, arm pain, Article, autism, child, chronic pain, cohort analysis, comorbidity, disease association, follow up, foot pain, hand pain, headache, health education, high risk patient, hip pain, human, knee pain, longitudinal study, low back pain, major clinical study, neck pain, nociception, outcome assessment, pain assessment, prevalence, prospective study, quality of life, risk reduction, shoulder pain, stomach pain, Swedish citizen, thorax pain
Subject categories Psychiatry, Neurochemistry

Abstract

Purpose: To investigate the prevalence of chronic pain and its association with healthrelated quality of life (HRQoL) in a group of women, diagnosed with autism spectrum disorder (ASD) and/or attention deficit hyperactive disorder (ADHD) in childhood. Patients and methods: Prospective longitudinal 16-19 years follow-up study of 100 Swedish females diagnosed with ASD and/or ADHD in childhood/adolescence. Seventyseven of the women were included in the current sub-study, using validated measures of pain perception and quality of life. Results: A large majority of the women (76.6%) reported chronic pain. HRQoL was low overall and lower still for those reporting chronic pain. Women with ADHD who had ongoing treatment with stimulants reported a significant lower prevalence of chronic widespread pain (CWP) than those not treated. Conclusion: Comorbidity with chronic pain is common in women with ASD and/or ADHD and important to address in the clinic since it is associated with an already low HRQoL. Treatment for ADHD might reduce the pain in some cases. © 2019 Asztély et al.

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