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ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection.

Journal article
Authors Shahab Nozohoor
Khalil Ahmad
Markus Bjurbom
Emma C. Hansson
Alexandra Heimisdottir
Anders Jeppsson
Ari Mennander
Christian Olsson
Emily Pan
Sigurdur Ragnarsson
Johan Sjögren
George Tellides
Anders Wickbom
Arnar Geirsson
Tomas Gudbjartsson
Igor Zindovic
Published in Scandinavian cardiovascular journal : SCJ
Pages 1-6
ISSN 1651-2006
Publication year 2019
Published at Institute of Medicine, Department of Molecular and Clinical Medicine
Pages 1-6
Language en
Links dx.doi.org/10.1080/14017431.2019.16...
www.ncbi.nlm.nih.gov/entrez/query.f...
Subject categories Clinical Medicine

Abstract

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7-43.4)% vs 39.0 (95% CI 39.0-39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

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