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Exposure to chlorpyrifos at different ages triggers APOE genotype-specific responses in social behavior, body weight and hypothalamic gene expression

Journal article
Authors P. Basaure
L. Guardia-Escote
J. Biosca-Brull
J. Blanco
M. Cabre
Fiona Peris-Sampedro
F. Sanchez-Santed
J. L. Domingo
M. T. Colomina
Published in Environmental Research
Volume 178
ISSN 0013-9351
Publication year 2019
Published at Institute of Neuroscience and Physiology, Department of Physiology
Language en
Links dx.doi.org/10.1016/j.envres.2019.10...
Keywords Social behavior, Feeding control, APOE genotype, Chlorpyrifos, Gene x, environmental factor, apolipoprotein-e gene, developmental exposure, targeted replacement, insecticide chlorpyrifos, aggressive-behavior, pesticide exposure, chronic dietary, oxytocin, level, polymorphisms, Environmental Sciences & Ecology, Public, Environmental & Occupational, Health
Subject categories Environmental Health and Occupational Health

Abstract

To date, we have shown that apolipoprotein E (APOE) polymorphisms differentially modulate the

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