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A biological or a synthetic mesh in immediate breast reconstruction? A cohort-study of long-term Health related Quality of Life (HrQoL)

Journal article
Authors Håkan Hallberg
Anna Elander
Lars Kölby
Emma Hansson
Published in European Journal of Surgical Oncology
Volume 45
Issue 10
Pages 1812-1816
ISSN 0748-7983
Publication year 2019
Published at Institute of Clinical Sciences, Department of Plastic Surgery
Pages 1812-1816
Language en
Keywords Acellular dermal matrix, Immediate breast reconstruction, Implant, Patient's satisfaction, Quality of life, Synthetic mesh, Tissue expander
Subject categories Plastic surgery


Objectives: Meshes/matrices are commonly used in immediate breast reconstruction. There are few studies comparing biological and synthetic meshes and it is unknown what type of mesh gives the best long-term results. The aim of this study was to compare long-term health-related quality of life (HrQoL) and patient satisfaction in implant-based immediate breast reconstruction with a biological mesh (Surgisis ® ) with that of patients reconstructed with a synthetic mesh (TIGR ® Matrix Surgical Mesh). Material and methods: Both cohorts were prospectively included and consecutively operated. Clinical data was collected. HrQoL was evaluated with EuroQoL-5 dimension – 3 levels questionnaire (EQ-5D-3L) and the Hospital Anxiety and Depression Scale (HADS) and the Breast-Q. Results and conclusion: Seventy-one patients were operated on in the biological group and 49 in the synthetic group. The response rates were 75 and 84 per cent, respectively. Mean follow-up time was 74 months and 23 months, respectively. There were no statistical differences in satisfaction and quality of life between the two groups. Complications and radiation seem to lead to a lower satisfaction. Our findings could indicate that biological and synthetic meshes give an equal long-term result as regards patients’ perceived quality of life.

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