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Contact allergy to beeswa… - University of Gothenburg, Sweden Till startsida
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Contact allergy to beeswax and propolis among patients with cheilitis or facial dermatitis.

Journal article
Authors Gunnar Nyman
Mimmi Tang
Annica Inerot
Amra Osmancevic
Per Malmberg
Lina Hagvall
Published in Contact Dermatitis
Volume 81
Issue 2
Pages 110-116
ISSN 0105-1873
Publication year 2019
Published at Institute of Clinical Sciences, Department of Dermatology and Venereology
Pages 110-116
Language en
Subject categories Dermatology and Venereal Diseases


Beeswax, both white and yellow, has many uses, as in lip balm. This material can cause contact allergy, although not many cases have been described.Ninety-five patients with contact cheilitis, facial eczema, or a suspicion of contact allergy to beeswax were patch-tested with yellow and white beeswax and with propolis in addition to the Swedish baseline series. Patients who tested positive to beeswax were additionally tested with caffeic acid, and two derivatives thereof which are believed to be important haptens in propolis.Seventeen patients had positive reactions to beeswax. Fourteen of those patients had been tested with both yellow and white beeswax. Among those fourteen, eight had positive reactions to both types of wax, five only to yellow and one only to white. Of the ten wax-positive patients tested with caffeic acid derivatives, three tested positive. Fourteen beeswax-positive patients also had positive reactions to propolis.Patch testing cheilitis patients is important as contact allergy is common. Our suggestion is to patch-test, except for the baseline series and the patient's own products, also with beeswax and propolis. Many of beeswax-allergic cheilitis patients had not been diagnosed with a relevant contact allergy if only the Swedish baseline series had been used. This article is protected by copyright. All rights reserved.

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