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Dental implants in patients with Sjögren's syndrome: a case series and a systematic review

Review article
Authors B. R. Chrcanovic
J. Kisch
Ann Wennerberg
Published in International Journal of Oral and Maxillofacial Surgery
Volume 48
Issue 9
Pages 1250-1259
ISSN 0901-5027
Publication year 2019
Published at Institute of Odontology
Pages 1250-1259
Language en
Keywords dental implant, failure, marginal bone loss, oral rehabilitation, Sjögren's syndrome
Subject categories Dentistry


The purpose of this study was to assess the clinical outcomes of dental implants in patients with Sjögren's syndrome (SS). The study consisted of two parts: report of a case series and a systematic review of the literature. The results of the clinical series revealed that 19 patients received 107 implants and were followed for a mean of 125 months. Two patients lost three implants (failure rate 2.8%, 3/107). At the last follow-up, there was a mean marginal bone loss (MBL) of −2.190 ± 1.384 mm; estimated MBL after 30 years was 4.39 mm. The review identified 18 studies, resulting in 19 studies for analysis including the present clinical series. A total of 712 implants were placed in 186 patients; 705 implants were followed up for a mean of 72.5 months (failure rate 4.1%, 29/705; failed at a mean time of 12.9 ± 31.7 months). The probability of failure was 2.8% (95% confidence interval 1.6–4.1%). Primary SS patients had a lower implant failure rate (2.5%, 3/118) than secondary SS patients (6.5%, 12/184). In conclusion, dental implants should be considered by dentists as a viable treatment option for patients with SS, as the failure rate is fairly low. SS patients may, however, present a higher MBL around implants than patients from the general population. © 2019 International Association of Oral and Maxillofacial Surgeons

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