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Symptom Clusters in Patients With Brain Tumors Undergoing Proton Beam Therapy.

Journal article
Authors Ulrica Langegård
Birgitta Johansson
Thomas Bjork-Eriksson
Per Fransson
Emma Ohlsson-Nevo
Katarina Sjövall
Karin Ahlberg
Published in Oncology nursing forum
Volume 46
Issue 3
Pages 349-363
ISSN 1538-0688
Publication year 2019
Published at Institute of Health and Care Sciences
Pages 349-363
Language en
Subject categories Nursing


To explore symptom clusters during proton beam therapy in patients with primary brain tumors and investigate associations among symptom clusters, demographic variables, and comorbidity in this patient population.Data were collected from 187 adult patients with primary brain tumors during their treatment periods in the Skandion Clinic in Uppsala, Sweden. Symptoms were assessed with the Radiotherapy-Related Symptoms Assessment Scale, and comorbidity was evaluated with the Self-Administered Comorbidity Questionnaire.The study used a quantitative and longitudinal design. Exploratory factor analysis was used to determine the underlying structure of symptom clusters.Three clusters were identified.Building knowledge about how these symptoms interact and are clustered will support healthcare professionals to more efficiently relieve symptom clusters during proton beam therapy.

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