To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

International validation … - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

International validation of the revised European Organisation for Research and Treatment of Cancer Head and Neck Cancer Module, the EORTC QLQ-HN43: Phase IV.

Journal article
Authors Susanne Singer
Cecilie Delphin Amdal
Eva Hammerlid
Iwona M Tomaszewska
Joaquim Castro Silva
Hisham Mehanna
Marcos Santos
Johanna Inhestern
Christine Brannan
Noam Yarom
Amy Fullerton
Monica Pinto
Juan I Arraras
Naomi Kiyota
Pierluigi Bonomo
Allen C Sherman
Ingo Baumann
Razvan Galalae
Loreto Fernandez Gonzalez
Ourania Nicolatou-Galitis
Zeinab Abdel-Hafeez
Judith Raber-Durlacher
Claudia Schmalz
Paola Zotti
Andreas Boehm
Dirk Hofmeister
Sanja Krejovic Trivic
Suat Loo
Wei-Chu Chie
Kristin Bjordal
Bente Brokstad Herlofson
Vincent Grégoire
Lisa Licitra
Published in Head & neck
Volume 41
Issue 6
Pages 1725-1737
ISSN 1097-0347
Publication year 2019
Published at Institute of Clinical Sciences, Department of Otorhinolaryngology
Institute of Clinical Sciences
Pages 1725-1737
Language en
Subject categories Cancer and Oncology


We validated the new European Organisation for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC QLQ-HN43).We enrolled 812 patients with head and neck cancer from 18 countries. Group 1 completed the questionnaire before therapy, and 3 and 6 months later. In group 2 (survivors), we determined test-retest reliability using intraclass correlation coefficients (ICC). Internal consistency was assessed using Cronbach's Alpha, the scale structure with confirmatory factor analysis, and discriminant validity with known-group comparisons.Cronbach's alpha was >0.70 in 10 of the 12 multi-item scales. All standardized factor loadings exceeded 0.40. The ICC was >0.70 in all but two scales. Differences in scale scores between known-groups were >10 points in 17 of the 19 scales. Sensitivity to change was found to be sufficient in 18 scales.Evidence supports the reliability and validity of the EORTC QLQ-HN43 as a measure of quality of life.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?