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Treatment of hepatitis C virus infection for adults and children: updated Swedish consensus guidelines 2017

Journal article
Authors Martin Lagging
Rune Wejstål
A. S. Duberg
S. Aleman
O. Weiland
Johan Westin
Published in Infectious Diseases
Volume 50
Issue 8
Pages 569-583
ISSN 2374-4235
Publication year 2018
Published at Institute of Biomedicine, Department of Infectious Medicine
Pages 569-583
Language en
Keywords Hepatitis C virus, HCV, Guidelines, Direct-acting antiviral agents, Ribavirin, Genotype, People who inject drugs, PWIDs, Children, Chronic, kidney disease, HIV, Elimination, Eradication, Resistance associated, variants (RAVs), Resistance associated substitutions (RASs), genotype 1 infection, daclatasvir plus sofosbuvir, treatment-experienced, patients, treatment-naive patients, severe renal impairment, fixed-dose, combination, open-label, hcv infection, hepatocellular-carcinoma, phase-3 trial, Infectious Diseases
Subject categories Infectious Medicine


Aim: Following the approval of two new therapeutic combinations within the European Union in 2017, the former Swedish recommendations for the treatment of hepatitis C virus (HCV) infection from 2016 were deemed in need of updating. Materials and methods: An expert meeting to this end was held in Stockholm, Sweden in October 2017. Results and conclusions: An interferon-free combination of direct-acting antiviral agents is now recommended for all patients with chronic HCV infection, regardless of liver fibrosis stage, in order to limit morbidity and spread of the disease. An extended discussion of treatment for people who inject drugs in order to diminish transmission is included.

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