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Cohort differences in the association of cardiovascular risk and cognitive aging

Journal article
Authors Peter Karlsson
Boo Johansson
Ingmar Skoog
Johan Skoog
Lina Rydén
Valgeir Thorvaldsson
Published in GeroPsych: The Journal of Gerontopsychology and Geriatric Psychiatry
Volume 31
Issue 4
Pages 195-203
ISSN 1662-9647
Publication year 2018
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Department of Psychology
Centre for Ageing and Health (Agecap)
Pages 195-203
Language en
Links https://doi.org/10.1024/1662-9647/a...
https://gup.ub.gu.se/file/207748
Subject categories Psychology (excluding Applied Psychology), Psychology

Abstract

Abstract. Aim: To investigate birth cohort differences in associations between cardiovascular risk and fluid cognition between the age of 70 and 79. Method: Data were drawn from representative population-based cohort samples (H70), born 1901–1902, 1906–1907, and 1930, measured at ages 70, 75, and 79 on fluid cognitive measures (spatial ability and logical reasoning). The Framingham Risk Score (FRS), derived from office-based nonlaboratory predictors (age, sex, systolic blood pressure, BMI, smoking, diabetes status), was used to measure cardiovascular risk. Multiple-group latent growth curve models were fitted to the data. Findings: Estimates revealed small associations between the FRS and fluid cognition. These associations were slightly reduced in the 1930 cohort. Conclusion: Findings suggest diminishing adverse effects of cardiovascular risk on cognitive aging in cohorts born later.

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