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[Epilepsy and comorbid neurodevelopmental disorders]

Review article
Authors Viviann Nordin
Ingrid Olsson
Torbjörn Tomson
Published in Läkartidningen
Volume 115
Issue Maj
Pages 928-930
ISSN 0023-7205
Publication year 2018
Published at Institute of Clinical Sciences, Department of Pediatrics
Pages 928-930
Language sv
Links https://www.ncbi.nlm.nih.gov/pubmed...
https://www.ncbi.nlm.nih.gov/pubmed...
Keywords Anticonvulsants/adverse effects Anticonvulsants/therapeutic use Antidepressive Agents/adverse effects Antidepressive Agents/therapeutic use Attention Deficit Disorder with Hyperactivity/drug therapy Attention Deficit Disorder with Hyperactivity/epidemiology Autistic Disorder/epidemiology Central Nervous System Stimulants/adverse effects Central Nervous System Stimulants/therapeutic use
Subject categories Neurology

Abstract

In children and adults with epilepsy, it is important to be aware of and diagnose common comorbidities that may have a large impact on quality of life. Comorbid neurodevelopmental disorders include intellectual disability, autism, and attention deficit hyperactivity disorder (ADHD). Depression and anxiety are common findings, and also the risk of psychosis is increased. The medication used to treat these comorbidities is found to be effective with little risks of seizure exacerbation, i.e. medication with methylphenidate, selective serotonin reuptake inhibitors (SSRIs) and second generation neuroleptics. However, for every combination of antiepileptic drugs with new medication, the possibility of drug interactions should be kept in mind. Transition from childhood to adult medicine must include adequate treatment and follow-up of comorbid conditions.

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