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Glycomics@ExPASy: Bridging the gap

Journal article
Authors J. Mariethoz
D. Alocci
A. Gastaldello
O. Horlacher
E. Gasteiger
Miguel A. Rojas-Macias
Niclas G. Karlsson
N. H. Packer
F. Lisacek
Published in Molecular and Cellular Proteomics
Volume 17
Issue 11
Pages 2164-2176
ISSN 1535-9476
Publication year 2018
Published at Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology
Pages 2164-2176
Language en
Links dx.doi.org/10.1074/mcp.RA118.000799
Keywords bioinformatics, glycobiology, human, philosophy, scientist, vision
Subject categories Bioinformatics and Systems Biology

Abstract

Glycomics@ExPASy (https://www.expasy.org/glycomics) is the glycomics tab of ExPASy, the server of SIB Swiss Institute of Bioinformatics. It was created in 2016 to centralize web-based glycoinformatics resources developed within an international network of glycoscientists. The hosted collection currently includes mainly databases and tools created and maintained at SIB but also links to a range of reference resources popular in the glycomics community. The philosophy of our toolbox is that it should be {glycoscientist AND protein scientist}-friendly with the aim of (1) popularizing the use of bioinformatics in glycobiology and (2) emphasizing the relationship between glycobiology and protein-oriented bioinformatics resources. The scarcity of data bridging these two disciplines led us to design tools as interactive as possible based on database connectivity to facilitate data exploration and support hypothesis building. Glycomics@ExPASy was designed, and is developed, with a long-term vision in close collaboration with glycoscientists to meet as closely as possible the growing needs of the community for glycoinformatics. © 2018 Mariethoz et al.

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