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Switched CD21-/low B cells with an antigen-presenting phenotype in the infant thymus.

Journal article
Authors Christina Lundqvist
Alessandro Camponeschi
Marcella Visentini
Esbjörn Telemo
Olov Ekwall
Inga-Lill Mårtensson
Published in The Journal of allergy and clinical immunology
Volume 143
Issue 4
Pages 1616-1620.e7
ISSN 1097-6825
Publication year 2019
Published at Institute of Medicine, Department of Rheumatology and Inflammation Research
Institute of Clinical Sciences, Department of Pediatrics
Pages 1616-1620.e7
Language en
Subject categories Immunology in the medical area


Half of all B cells in the human thymus are mature CD21-/low AIRE-expressing cells with a professional antigen presenting cell phenotype, implying a role in T-cell selection and therefore critical in preventing autoimmunity.

Page Manager: Webmaster|Last update: 9/11/2012

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