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Viewpoint and practical recommendations from a movement disorder specialist panel on objective measurement in the clinical management of Parkinson's disease

Journal article
Authors P. Odin
K. R. Chaudhuri
J. Volkmann
A. Antonini
A. Storch
E. Dietrichs
Z. Pirtosek
T. Henriksen
M. Horne
D. Devos
Filip Bergquist
Published in Npj Parkinson's Disease
Volume 4
ISSN 2373-8057
Publication year 2018
Published at Institute of Neuroscience and Physiology, Department of Pharmacology
Language en
Keywords quality-of-life, medication adherence, motor fluctuations, care, outcomes, impact, costs, trial, complications, dyskinesias, Neurosciences & Neurology
Subject categories Neurosciences


Motor aspects of Parkinson's disease, such as fluctuations and dyskinesia, can be reliably evaluated using a variety of "wearable" technologies, but practical guidance on objective measurement (OM) and the optimum use of these devices is lacking. Therefore, as a first step, a panel of movement disorder specialists met to provide guidance on how OM could be assessed and incorporated into clinical guidelines. A key aspect of the incorporation of OM into the management of Parkinson's disease (PD) is defining cutoff values that separate "controlled" from "uncontrolled" symptoms that can be modified by therapy and that relate to an outcome that is relevant to the person with PD (such as quality of life). Defining cutoffs by consensus, which can be subsequently tested and refined, is the first step to optimizing OM in the management of PD. OM should be used by all clinicians that treat people with PD but the least experienced may find the most value, but this requires guidance from experts to allow non-experts to apply guidelines. While evidence is gained for devices that produce OM, expert opinion is needed to supplement the evidence base.

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