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Detection of "Xisco" gene for identification of Streptococcus pneumoniae isolates

Journal article
Authors Francisco Salvà-Serra
Gwendolyn Connolly
Edward R.B. Moore
Lucia Gonzales-Siles
Published in Diagnostic Microbiology and Infectious Disease
Volume 90
Issue 4
Pages 248-250
ISSN 0732-8893
Publication year 2018
Published at Centre for antibiotic resistance research, CARe
Institute of Biomedicine, Department of Infectious Medicine
Pages 248-250
Language en
Keywords "Xisco" gene, Streptococcus pneumoniae, Pneumococcus, Identification, Mitis group, PCR, genome sequence, mitis, Infectious Diseases, Microbiology
Subject categories Microbiology in the medical area


We describe a PCR-assay differentiating Streptococcus pneumoniae from closely-related species of the Mitis group of the genus Streptococcus and identification of pneumococcus clinical isolates, based on the "Xisco" gene discriminatory marker. The complete "Xisco" gene sequence was observed in all S. pneumoniae genomes analyzed and absent in all non-pneumococcus genomes.

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