To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Positron emission tomogra… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Positron emission tomography and computed tomographic (PET/CT) imaging for radiation therapy planning in anal cancer: A systematic review and meta-analysis

Review article
Authors Per Albertsson
Charlotte Alverbratt
Ann Liljegren
Emil Björkander
Annika Strandell
Ola Samuelsson
Stig Palm
Andreas Hallqvist
Published in Critical reviews in oncology/hematology
Volume 126
Pages 6-12
ISSN 1040-8428
Publication year 2018
Published at Institute of Clinical Sciences, Department of Radiation Physics
Pages 6-12
Language en
Keywords Anal cancer, Meta-analysis, PET/CT, Radiotherapy
Subject categories Cancer and Oncology


To improve the accuracy of chemoradiation therapy in anal cancer patients PET/CT is frequently used in the planning of radiation therapy. A systematic review was performed to assess impact on survival, quality of life, symptom score, change in target definition and treatment intention. Systematic literature searches were conducted in Medline, EMBASE, the Cochrane Library, and Centre for Reviews and Dissemination. Ten cross-sectional studies were identified. No data were available on survival or quality of life. The summary estimate of the proportion of patients in which PET/CT had an impact on the target definition, was 23% (95% CI 16;33). The corresponding summary estimate of a change in treatment intent from curative to palliative was 3% (95% CI 2;6). Almost one in four patients had a change in target definition, which supports the use of PET/CT in radiation therapy planning, but the consequence regarding survival and quality of life is still uncertain.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?