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Clinical characterization of women with burning mouth syndrome in a case-control study.

Journal article
Authors Shikha Acharya
Anette Carlén
Bengt Wenneberg
Mats Jontell
Catharina Hägglin
Published in Acta Odontologica Scandinavica
Volume 76
Issue 4
Pages 279-86
ISSN 1502-3850
Publication year 2017
Published at Institute of Odontology
Institute of Odontology, Section 1
Institute of Odontology, Section 3
Pages 279-86
Language en
Keywords Burning Mouth Syndrome
Subject categories Dentistry


Burning mouth syndrome (BMS) is a chronic orofacial pain disorder that is defined by a burning sensation in the oral mucosa. The aim of this study was to investigate the underlying factors, clinical characteristics and self-reported oral and general health factors associated with BMS.Fifty-six women with BMS (mean age: 67.7) and their age-matched controls were included in the study. A general questionnaire, an OHRQL index and BMS-specific questionnaires were used. Each subject underwent an oral examination.The mean severity of the BMS symptoms (VAS, 0-100) was 66.2 (SD 19.7). Overall, 45% of the patients reported taste disturbances. More of the patients than the controls rated their general health, oral health and life situation as 'less satisfactory'. The patients also reported more frequently on-going medications, diseases/disorders, xerostomia, allergy and skin diseases. Except for more bruxofacets among the patients, there were no significant differences regarding signs of parafunction. In a multiple logistic regression analysis, xerostomia and skin diseases showed the strongest prediction for BMS and no significant effect was found for medication, allergy or bruxofacets.Skin diseases and xerostomia but not parafunction were strongly associated with BMS. Our findings provide the basis for additional studies to elucidate the causal factors of BMS.

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