To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Neuromodulation via the C… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

Neuromodulation via the Cerebrospinal Fluid: Insights from Recent in Vitro Studies.

Journal article
Authors Andreas Björefeldt
Sebastian Illes
Henrik Zetterberg
Eric Hanse
Published in Frontiers in neural circuits
Volume 12
ISSN 1662-5110
Publication year 2018
Published at Institute of Neuroscience and Physiology, Department of Physiology
Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Language en
Subject categories Neurochemistry


The cerebrospinal fluid (CSF) occupies the brain's ventricles and subarachnoid space and, together with the interstitial fluid (ISF), forms a continuous fluidic network that bathes all cells of the central nervous system (CNS). As such, the CSF is well positioned to actively distribute neuromodulators to neural circuitsin vivovia volume transmission. Recentin vitroexperimental work in brain slices and neuronal cultures has shown that human CSF indeed contains neuromodulators that strongly influence neuronal activity. Here we briefly summarize these new findings and discuss their potential relevance to neural circuits in health and disease.

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?