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Clinical performance of dental implants with a moderately rough (TiUnite) surface: A meta-analysis of prospective clinical studies

Journal article
Authors M. Karl
Tomas Albrektsson
Published in International Journal of Oral and Maxillofacial Implants
Volume 32
Issue 4
Pages 717-734
ISSN 0882-2786
Publication year 2017
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 717-734
Language en
Keywords Implant surface, Implant survival rate, Marginal bone level change, Meta-analysis, Moderately rough, Prospective clinical study
Subject categories Dentistry, Biomaterials Science


Purpose: A moderately rough anodized titanium implant surface (TiUnite) was introduced in 2000. This review and meta-analysis aimed to assess implant survival and marginal bone level (MBL) changes documented in the literature. Materials and Methods: Repeated literature searches on dental implants were conducted, with the final search on October 7, 2016. The inclusion criteria were: prospective study, minimum of 20 patients, at least 12 months follow-up postloading, and TiUnite implant survival reported. Regression analysis was performed on implant survival and MBL change from implant surgery. Peri-implantitis as defined by the primary authors was reported at the patient level. Results: One hundred six out of 32,519 publications on dental implants met the inclusion criteria. Implant survival rates at 1 year were 99.50% at the implant level and 99.12% at the patient level, and survival rates at 10 years were 95.14% at the implant level and 91.50% at the patient level. Mean MBL change at 1 year was -0.409 mm at the implant level and -0.413 mm at the patient level, and at 5 years, it was -0.886 mm at the implant level and -1.029 mm at the patient level. Nineteen studies (18%) specifically reported peri-implantitis in 64 out of 1,229 patients with a mean followup of 47.89 months, indicating a prevalence of 5.20% at the patient level. Conclusion: Based on a metaanalysis of prospective studies, implants with the TiUnite surface provide a predictable treatment modality in a variety of indications. © 2017 by Quintessence Publishing Co Inc.

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