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Lateral ridge augmentation with Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone graft: a systematic review

Journal article
Authors H. C. Aludden
A. Mordenfeld
M. Hallman
Christer Dahlin
T. Jensen
Published in International Journal of Oral and Maxillofacial Surgery
Volume 46
Issue 8
Pages 1030-1038
ISSN 0901-5027
Publication year 2017
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 1030-1038
Language en
Keywords alveolar ridge augmentation, Bio-Oss, bone substitute, dental implants, systematic review, partially edentulous patients, deproteinized bovine bone, sinus floor, augmentation, prospective case series, implant placement, pathological, research, collagen membranes, atrophic maxilla, clinical-trial, onlay, graft, Dentistry, Oral Surgery & Medicine, Surgery
Subject categories Dentistry


The objective of this systematic review was to test the hypothesis of no difference in implant treatment outcomes when using Bio-Oss alone or Bio-Oss mixed with particulate autogenous bone grafts for lateral ridge augmentation. A search of the MEDLINE, Cochrane Library, and Embase databases in combination with a hand-search of relevant journals was conducted. Human studies published in English from 1 January 1990 to 1 May 2016 were included. The search provided 337 titles and six studies fulfilled the inclusion criteria. Considerable variation prevented a meta-analysis from being performed. The two treatment modalities have never been compared within the same study. Non-comparative studies demonstrated a 3-year implant survival of 96% with 50% Bio-Oss mixed with 50% autogenous bone graft. Moreover, Bio-Oss alone or Bio-Oss mixed with autogenous bone graft seems to increase the amount of newly formed bone as well as the width of the alveolar process. Within the limitations of this systematic review, lateral ridge augmentation with Bio-Oss alone or in combination with autogenous bone graft seems to induce newly formed bone and increase the width of the alveolar process, with high short-term implant survival. However, long-term studies comparing the two treatment modalities are needed before final conclusions can be drawn.

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