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Risk of Heart Failure in Obese Patients With and Without Bariatric Surgery in Sweden-A Registry-Based Study

Journal article
Authors Christina Persson
Lena Björck
Georg Lappas
Kok Wai Giang
Annika Rosengren
Published in Journal of Cardiac Failure
Volume 23
Issue 7
Pages 530-537
ISSN 1071-9164
Publication year 2017
Published at Institute of Health and Care Sciences
Institute of Medicine, Department of Molecular and Clinical Medicine
Pages 530-537
Language en
Links https://doi.org/10.1016/j.cardfail....
Keywords Heart failure, obesity, bariatric surgery, mortality, epidemiology, lifetime risk, weight-loss, epidemiology, validation, mortality, diagnosis, adults, Cardiovascular System & Cardiology
Subject categories Clinical Medicine

Abstract

Background: Obesity is a known risk factor for heart failure. The prevalence of both conditions has increased in Sweden during the past several decades. Obesity surgery has been shown to improve cardiac function. We therefore investigated whether the risk of heart failure was lower in obese patients after bariatric surgery compared with obese patients without surgical intervention. Methods and results: From the Swedish National Patient Registry. we created a cohort including 47,859 patients aged 18-74 years with a primary diagnosis of obesity from 2000 to 2011. Of these, 22,295 (46.6%) underwent bariatric surgery (mean age 40.7 (standard deviation [SD] 10.7) years, 75.9% female). There were 25,564 (53.4%) nonsurgical obese patients (mean age 44.3 (SD 13.2) years, 66.8% female). Patients who underwent bariatric surgery had a markedly reduced risk of heart failure compared with nonsurgical obese patients (age- and sex-adjusted hazard ratio [HR] 0.37, 95% confidence interval [CI] 0.29-0.46). The lower risk persisted after further adjustment for baseline differences in known risk factors for heart failure (HR 0.37, 95% CI 0.30-0.46). Conclusion: Patients who underwent bariatric surgery had a reduced risk of heart failure after surgery compared with nonsurgical obese patients.

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