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Hard tissue response

Chapter in book
Authors Tomas Albrektsson
Published in Murphy W., Black J., Hastings G. (eds) Handbook of Biomaterial Properties.
Pages 581-592
ISBN 978-1-4939-3303-7
Publication year 2016
Published at Institute of Clinical Sciences, Department of Biomaterials
Pages 581-592
Language en
Subject categories Biomaterials Science


The initial tissue response when a biomaterial is implanted in the body is dependent on release of specific growth factors. It has been indicated by Frost [1] that the inevitable bone injury resulting from surgery and the presence of an implant will release various types of growth factors that will sensitize cells and promote cellular mitosis. This is a general healing response that will result in growth of all sorts of local connective tissues, bone as well as various types of soft tissue. © Springer Science+Business Media New York 2016.

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