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Aortic diameter at age 65 in men with newly diagnosed type 2 diabetes

Journal article
Authors S. Taimour
M. Zarrouk
J. Holst
Anders H. Rosengren
L. Groop
P. M. Nilsson
A. Gottsater
Published in Scandinavian Cardiovascular Journal
Volume 51
Issue 4
Pages 202-206
ISSN 1401-7431
Publication year 2017
Published at Institute of Neuroscience and Physiology
Pages 202-206
Language en
Keywords Abdominal aortic aneurysm, aortic diameter, type 2 diabetes, ultrasound, screening, aneurysm screening-program, arterial territories, risk-factors, management, disease, association, mortality, atherosclerosis, epidemiology, dysfunction, Cardiovascular System & Cardiology
Subject categories Epidemiology, Cardiovascular medicine


Objectives. Type 2 diabetes mellitus has been linked to a decreased risk for abdominal aortic aneurysm (aortic diameter 30mm, AAA) development in men. The aim of this study was to evaluate if such an effect is detectable already around the time of diabetes diagnosis. Design. We cross-sectionally compared aortic diameter at ultrasound screening for AAA in 691 men aged 65 years with incipient or newly diagnosed type 2 diabetes (group A) with 18,262 65-year old control men without diabetes (group B). Results. Aortic diameter did not differ between groups (18.8[17.4-20.8] vs. 19.0[17.5-28.7] mm; p=0.43). AAA prevalence was 2.5% in group A and 1.5% in group B (p=.010). In logistic regression taking group differences in body mass index (BMI), smoking, presence of atherosclerotic disease and hypertension into account, the difference in AAA prevalence was no longer significant (p=.15). Among men in group A, C-peptide (r=.093; p=.034), but not HbA1c (r=.060; p=.24) correlated with aortic diameter. Conclusion. Among 65 year old men aortic diameter and AAA prevalence do not differ between those with newly diagnosed type 2 diabetes and those without diabetes. Putative protective effects of type 2 diabetes mellitus against aortic dilatation and AAA development therefore probably occur later after diagnosis of diabetes.

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