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Treatment of hepatitis C virus infection: updated Swedish Guidelines 2016.

Journal article
Authors Martin Lagging
Rune Wejstål
Gunnar Norkrans
Olle Karlström
Soo Aleman
Ola Weiland
Maria Castedal
Johan Westin
Published in Infectious diseases (London, England)
Volume 49
Issue 8
Pages 561-575
ISSN 2374-4243
Publication year 2017
Published at Institute of Clinical Sciences, Department of Surgery
Institute of Biomedicine, Department of Infectious Medicine
Pages 561-575
Language en
Links dx.doi.org/10.1080/23744235.2017.13...
www.ncbi.nlm.nih.gov/entrez/query.f...
Subject categories Infectious Medicine

Abstract

In a recent expert meeting, Swedish recommendations for the treatment of hepatitis C virus (HCV) infection were updated. An interferon-free combination of direct-acting antiviral agents is considered and indicated for all patients with chronic HCV infection, but the ability to treat all is limited primarily by high cost of medication. The group of patients prioritized for therapeutic intervention has been extended to also include fertile women desiring to become pregnant. A more thorough discussion of treatment for people who inject drugs (PWIDs) in order to diminish transmission is included, and the clinical significance of baseline NS5A resistance associated variants (RAVs), also known as resistance associated substitutions (RASs), for the treatment of HCV genotype 1a or 3 infection is discussed.

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