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The Effect of Normovolemic and Hypervolemic Hemodilution on a Perforator Flap with Twisted Pedicle Model: Experimental Study in Rats.

Journal article
Authors Matteo Amoroso
Özlenen Özkan
Cumhur İbrahim Başsorgun
Önur Ögan
Kerim Ünal
Benedetto Longo
Fabio Santanelli di Pompeo
Ömer Özkan
Published in Plastic and reconstructive surgery
Volume 137
Issue 2
Pages 339e-346e
ISSN 1529-4242
Publication year 2016
Published at
Pages 339e-346e
Language en
Keywords Animals, Female, Graft Survival, Hemodilution, methods, Perforator Flap, blood supply, Rats, Rats, Wistar, Torsion, Mechanical
Subject categories Plastic surgery


Several studies showed the detrimental effect of pedicle torsion on flap survival; however, the impact of hemodilution in this peculiar condition has never been investigated. This study evaluated the effect of acute normovolemic and hypervolemic hemodilution on flap survival in a perforator flap with twisted pedicle model.

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