To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Cardiovascular events aft… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

Cardiovascular events after ischemic stroke in young adults: A prospective follow-up study

Journal article
Authors K. Aarnio
B. Siegerink
J. Pirinen
J. Sinisalo
M. Lehto
E. Haapaniemi
A. H. Nave
M. Kaste
Turgut Tatlisumak
J. Putaala
Published in Neurology
Volume 86
Issue 20
Pages 1872-1879
ISSN 0028-3878
Publication year 2016
Published at Institute of Neuroscience and Physiology
Pages 1872-1879
Language en
Links dx.doi.org/10.1212/wnl.000000000000...
Keywords HOSPITAL DISCHARGE REGISTER, RECURRENT VASCULAR EVENTS, LONG-TERM, PROGNOSIS, ATHEROSCLEROTIC DISEASE, VENOUS THROMBOEMBOLISM, RISK, POPULATION, DEATH, AGE, CLASSIFICATION
Subject categories Neurosciences

Abstract

Objectives:To study the long-term risk of recurrent cardiac, arterial, and venous events in young stroke patients, and whether these risks differed between etiologic subgroups.Methods:The study population comprised 970 patients aged 15-49 years from the Helsinki Young Stroke Registry (HYSR) who had an ischemic stroke in 1994-2007. We obtained follow-up data until 2012 from the Finnish Care Register and Statistics Finland. Cumulative 15-year risks were analyzed with life tables, whereas relative risks and corresponding confidence intervals (CI) were based on hazard ratios (HR) from Cox regression analyses.Results:There were 283 (29.2%) patients with a cardiovascular event during the median follow-up of 10.1 years (range 0.1-18.0). Cumulative 15-year risk for venous events was 3.9%. Cumulative 15-year incidence rate for composite vascular events was 34.0 (95% CI 30.1-38.2) per 1,000 person-years. When adjusted for age and sex, patients with an index stroke caused by high-risk sources of cardioembolism had the highest HR for any subsequent cardiovascular events (3.7; 95% CI 2.6-5.4), whereas the large-artery atherosclerosis group had the highest HR (2.7; 95% CI 1.6-4.6) for recurrent stroke compared with patients with stroke of undetermined etiology.Conclusions:The risk for future cardiovascular events after ischemic stroke in young adults remains high for years after the index stroke, in particular when the index stroke is caused by high-risk sources of cardioembolism or large-artery atherosclerosis.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?