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Improved bone ingrowth and fixation with a thin calcium phosphate coating intended for complete resorption

Journal article
Authors O. Reigstad
Victoria Franke Stenport
Carina B. Johansson
Ann Wennerberg
Magne Røkkum
A. Reigstad
Published in Journal of Biomedical Materials Research - Part B Applied Biomaterials
Volume 83
Issue 1
Pages 9-15
ISSN 1552-4973
Publication year 2007
Published at Institute of Odontology
Institute of Clinical Sciences, Department of Biomaterials
Pages 9-15
Language en
Keywords Calcium phosphate
Subject categories Dentistry


Bonit® is claimed to be a resorbable electrochemically deposited calcium phosphate coating consisting mainly of brushite, which is a hydroxyapatite precursor. This study involved a comparison of Ti6Al4V screw-shaped implants with and without a 15 ± 5 μm Bonit coating in rabbit tibia and femur, after 6 and 12 weeks of insertion. The biomechanical removal torque test showed significantly increased values for the coated implants after 12 weeks (p < 0.05) but not after 6 weeks of integration. Higher bone-implant contact was found for the coated implants in the tibia after 6 weeks and for both tibial and femoral screws after 12 weeks (p < 0.05). There was no difference in the inflammatory reaction around the implants, and possible grains of the coating could be detected after 6 weeks, but not after 12 weeks of follow-up. This unloaded short-term study has shown promising results for the easily applicable and resorbable coat (Bonit) compared to uncoated titanium-alloy implants. © 2007 Wiley Periodicals, Inc.

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