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Cerebrospinal fluid biomarkers of inflammation and degeneration as measures of fingolimod efficacy in multiple sclerosis.

Journal article
Authors Lenka Novakova
Markus Axelsson
Mohsen Khademi
Henrik Zetterberg
Kaj Blennow
Clas Malmeström
Fredrik Piehl
Thomas Olsson
Jan Lycke
Published in Multiple sclerosis (Houndmills, Basingstoke, England)
Volume 23
Issue 1
Pages 62-71
ISSN 1477-0970
Publication year 2017
Published at Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Institute of Neuroscience and Physiology, Department of Clinical Neuroscience
Pages 62-71
Language en
Links dx.doi.org/10.1177/1352458516639384
Subject categories Neurochemistry

Abstract

The disease-modifying therapies (DMTs) in relapsing-remitting multiple sclerosis (RRMS) vary in their mode of action and when therapies are changed, the consequences on inflammatory and degenerative processes are largely unknown.

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