To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

The use of MgO-paste as a… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

The use of MgO-paste as a biodegradeable bone cement

Conference paper
Authors A. Biel
Mobina Chaudhry
Stefan Gustafsson
Håkan Nygren
Published in Materials Today-Proceedings
Volume 3
Issue 2
Pages 556-561
ISSN 2214-7853
Publication year 2016
Published at Institute of Biomedicine
Pages 556-561
Language en
Links dx.doi.org/10.1016/j.matpr.2016.01....
Keywords Bone formation, bone cement, Magnesium, bone healing, osteoporosis, magnesium
Subject categories Clinical Medicine

Abstract

The use of MgO-paste as bone cement was tested on titanium cylinders implanted into rat tibia. The evaluation of bone healing was made with the retention force (pull-out) test, light microscopy and ESEM/EDX. Preimplantation of the MgO-paste into drill perforations of rat tibia increased the retention of the titanium implant 6-fold. The error was expressed as the 95% confidence interval of means (n = 10 bones in each group). The observed difference between 3.46+/-0.71 N/mm(2) for Ti-cylinders implanted with MgO-paste and 0.56+/-0.26 N/mm(2) for Ti-cylinders implanted directly into the bone, is statistically significant (p < 0.01). The increase of retention force, caused by MgO is parallel to an increased thickness of the compact bone surrounding the implant and closer contact between bone and implant. Histological examination of the implant-related bone showed that the MgO-induced bone growth is mediated by the formation of a bone-inducing matrix. The matrix contains organic substance, most likely proteins.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?