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Body fat mass and the proportion of very large adipocytes in pregnant women are associated with gestational insulin resistance.

Journal article
Authors Henrik Svensson
Louise Wetterling
Marja Bosaeus
Birgitta Odén
Anders Odén
Eva Jennische
Staffan Edén
Agneta Holmäng
Malin Lönn
Published in International journal of obesity (2005)
Volume 40
Pages 646-653
ISSN 1476-5497
Publication year 2016
Published at Institute of Neuroscience and Physiology, Department of Physiology
Institute of Biomedicine, Department of Clinical Chemistry and Transfusion Medicine
Department of Mathematical Sciences, Mathematical Statistics
Institute of Medicine
Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology
Pages 646-653
Language en
Links dx.doi.org/10.1038/ijo.2015.232
Subject categories Physiology, Cell biology, Morphology

Abstract

Pregnancy is accompanied by fat gain and insulin resistance. Changes in adipose tissue morphology and function during pregnancy and factors contributing to gestational insulin resistance are incompletely known. We sought to characterize adipose tissue in trimesters 1 and 3 (T1/T3) in normal weight (NW) and obese pregnant women, and identify adipose tissue-related factors associated with gestational insulin resistance.

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