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Treatment of hepatitis C virus infection for adults and children: Updated Swedish consensus recommendations.

Magazine article
Authors Martin Lagging
Rune Wejstål
Gunnar Norkrans
Olle Karlström
Soo Aleman
Ola Weiland
Maria Castedal
Filip Josephson
Published in Infectious diseases (London, England)
Volume 48
Issue 4
Pages 251-261
ISSN 2374-4243
Publication year 2016
Published at Institute of Clinical Sciences, Department of Surgery
Institute of Biomedicine, Department of Infectious Medicine
Pages 251-261
Language en
Links dx.doi.org/10.3109/23744235.2015.11...
Subject categories Infectious Medicine

Abstract

In a recent expert meeting, Swedish recommendations for the treatment of HCV infection were updated. An interferon-free combination of direct-acting antiviral agents was recommended as the first line standard-of-care treatment for chronic HCV infection. Interferon-based therapy should be considered as a second line option after an individual benefit-risk assessment. Treatment is strongly recommended for HCV infected patients with bridging fibrosis or cirrhosis (Metavir stages F3-4), before and after liver transplantation, and in the presence of extra-hepatic manifestations. Additionally, patients with moderate liver fibrosis (stage F2) as well as women in need of in vitro fertilisation should be prioritised for therapeutic intervention. Treatment indications for people who inject drugs, children, chronic kidney disease and HIV co-infection are also discussed.

Page Manager: Webmaster|Last update: 9/11/2012
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