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Comparison of Carisolv system vs traditional rotating instruments for caries removal in the primary dentition: A systematic review and meta-analysis

Journal article
Authors G. Lai
C. L. Capi
F. Cocco
M. G. Cagetti
Peter Lingström
Ulrica S. Almhöjd
G. Campus
Published in Acta Odontologica Scandinavica
Volume 73
Issue 8
Pages 569-580
ISSN 0001-6357
Publication year 2015
Published at Institute of Odontology
Institute of Odontology, Section 3
Pages 569-580
Language en
Keywords carisolv, chemo mechanical caries removal, dental caries, primary dentition, rotating instruments, clinical-evaluation, primary teeth, children, efficacy
Subject categories Dentistry


Objective. The purpose of this systematic review and meta-analysis was to evaluate the reliability of the Carisolv system with respect to drilling regarding the full removal of decayed hard tissues in primary dentition. A systematic review of the literature was conducted to identify controlled trails, randomized controlled trials and clinical trials that compared the Carisolv system to the traditional mechanical caries removal in the primary dentition. Materials and methods. The main relevant databases were searched: MEDLINE via PUBMED, Web of Science and SCOPUS. Complete caries removal, length of working time and need of local anesthesia were the outcomes evaluated. Results. A total of 195 studies were identified and complete analysis of 28 studies was performed; finally, 10 papers were included. The trials included involved a total of 348 patients for 532 treated teeth. There was no significant difference in terms of clinical efficacy between the Carisolv and the rotary instrument (z = 0.68, p = 0.50), whereas the treatment with Carisolv was significantly longer in terms of time with respect to the rotary instruments (z = 10.49, p < 0.01). The chemo mechanical technique reduces the need for local anesthesia, with a difference between two types of treatment near to statistical significance (z = 1.91 p = 0.06). Conclusions. This systematic review indicates that the clinical efficacy of chemo-mechanical removal with Carisolv seems as reliable as the rotary instruments. However, the results should be interpreted cautiously due to the heterogeneity among study designs and to the shortage of available data. Further large-scale, well-designed randomized controlled trials are needed.

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